Original air date: 11/03/2019 Runtime: 42:23 min. On the eve of the worldwide launch of Andrea Rojas's virtual reality contact lenses, Kara and William team up on an investigation that exposes a terrorist plot; Kelly and Alex celebrate an anniversary, but Alex's safety is in jeopardy.
Original air date: 12/01/2019 Runtime: 42:01 min. In the Mid-Season finale, Supergirl’s struggle against Leviathan reaches a boiling point as she faces off against Rama Khan (guest star MITCH PILEGGI). Meanwhile, Hope proves to be an invaluable asset to Lena as they work to launch Project Non Nocere.
Original air date: 02/23/2020 Runtime: 42:23 min. Mxyzptlk (guest star THOMAS LENNON) returns with a proposition for Kara – what if she could go back in time and tell Lena her secret before Lex did, would things turn out different? Looking back over key moments throughout the series, Kara must decide if she wants to change history to become friends with Lena again. Familiar faces return in this special 100th episode.
Original air date: 03/15/2020 Runtime: 42:15 min. Nia’s roommate, Yvette (guest star ROXY WOOD), is attacked by a man targeting Dreamer because he doesn’t like that Dreamer is transgender and wants her to quit being a superhero. Determined to protect her community from additional harm, Dreamer refuses to give in to his threats and puts herself in the line of fire to stop him. Supergirl stands by Dreamer and enlists additional help from Brainy. Meanwhile, Alex, J’onn and Kelly attempt to rescue a man stuck inside a virtual reality escape room.
Original air date: 05/03/2020 Runtime: 42:18 min. Lex proceeds to lay an intricate plan to bring Lena closer to him, defeat Leviathan’s latest attack, and pit Supergirl and team against Leviathan. It is also revealed how Lex came into power after Crisis. Series star Melissa Benoist makes her directorial debut.
Original air date: 05/17/2020 Runtime: 42:19 min. In the fifth season finale, Supergirl realizes that in order to stop Lex and Leviathan, she must work with the one person she never thought she’d trust again – Lena. Nia keeps dreaming about Brainy but struggles with what the dreams are trying to tell her. Meanwhile, Brainy realizes there is only one way to stop Lex. Series star David Harewood directs.