Original air date: 11/09/2020 Runtime: 43:08 min. Shaun has a hard time balancing his fears and concerns about potentially jeopardizing Lea's health and wanting to be with the woman he loves. Claire looks for a way to grieve Melendez's death. Park and Mia discuss their future together.
Original air date: 11/16/2020 Runtime: 42:50 min. With several candidates vying for residency at St. Bonaventure, Lim tasks Shaun, Claire and Alex with mentoring the top first-year resident contenders; Shaun inadvertently insults Lea while discussing the pros and cons of a controversial surgery.
Original air date: 11/30/2020 Runtime: 43:08 min. Dr. Murphy questions his decision to give the new residents autonomy when an intern's misdiagnosis has dire consequences; a patient has a ruptured cyst affecting key functions of her brain; Dr. Morgan Reznick and Park bond over failed relationships.
Original air date: 01/11/2021 Runtime: 42:16 min. Dr. Audrey Lim struggles to cope with the residual emotional trauma of COVID-19; Dr. Claire Browne suggests a radical treatment to help a war veteran who has PTSD; Dr. Shaun Murphy declares he doesn't want to teach the new residents any more.
Original air date: 02/22/2021 Runtime: 43:09 min. When the hospital is hit with a cyberattack threatening to shut down life-saving machines, Lea rises to the challenge and looks to outsmart the hackers to prove herself. Meanwhile, the team treats an inspirational cancer survivor-turned-successful-philanthropist who harbors a dark secret.
Original air date: 03/08/2021 Runtime: 43:08 min. After bringing in an incredibly unique and complicated spinal surgery, Dr. Aaron Glassman challenges the residents for an opportunity to join him in the operating room. Meanwhile, Shaun and Morgan disagree on how to treat a comatose patient with a cancerous tumor.
Original air date: 03/22/2021 Runtime: 43:09 min. When a renowned surgeon comes to St. Bonaventure for treatment, the team's enthusiasm is quickly overshadowed by the doctor's behavior; Shaun and Lea are forced to make a life-changing decision that will alter the course of their relationship.
Original air date: 04/19/2021 Runtime: 43:09 min. After finding out the gender of their unborn child, Lea's enthusiasm prompts Shaun to make an effort to be a more supportive partner. Meanwhile, the team treats a navy pilot whose previous doctor's misdiagnosis compromises her chances at a full recovery.
Original air date: 05/10/2021 Runtime: 43:05 min. Shaun struggles with his role as Lea's partner after complications arise with the pregnancy and his instincts as a medical professional kick in; Dr. Park, Dr. Andrews and Asher disagree on how to address an elderly patient's wishes.
Original air date: 05/31/2021 Runtime: 43:07 min. The team travels to Guatemala on a mission to help patients at a rural hospital; the team faces a small community that is in desperate need of help, but they must identify who they can help most; Lea is still struggling with the loss of her baby.