Original air date: 11/24/2015 Runtime: 40:50 min. As Dr. Ethan Choi (Brian Tee) treats a bleeding teenage girl, he discovers she's just given birth, sparking a frantic search for her abandoned baby. When the details of the teen's troubled past emerge, Ethan finds himself at odds with pediatrician Dr. Natalie Manning (Torrey DeVitto) and hospital administrator Sharon Goodwin (S. Epatha Merkerson) as they're forced to make some difficult decisions about the teen's future. Dr. Will Halstead (Nick Gehlfuss) treats a hypochondriac with chest pains while struggling to navigate his overbearing wife. Meanwhile, med student Sarah Reese (Rachel DiPillo) and psychiatrist Dr. Daniel Charles (Oliver Platt) treat a patient suffering from dementia, only to discover she may not have dementia at all.
Original air date: 12/01/2015 Runtime: 41:38 min. When Dr. Connor Rhodes (Colin Donnell) takes the case of a close family friend who's been impaled by glass shards, he's reunited with his sister, Claire Rhodes (guest start Christina Brucato), and forced to confront his past. Meanwhile, Dr. Natalie Manning (Torrey DeVitto) convinces a young musician to undergo a surgery that will save her life but could destroy her hearing.
Original air date: 12/08/2015 Runtime: 41:23 min. After shots ring out at a movie theater, the Chicago Med doctors work to treat the victims while hospital administrator Sharon Goodwin (S. Epatha Merkerson) attempts to keep the press at bay. To treat a teenager with an eating disorder, Dr. Natalie Manning (Torrey DeVitto) enlists the help of Dr. Daniel Charles (Oliver Platt), but his unorthodox methods rub Natalie and the teenage girl's mother the wrong way. Meanwhile, Nurse April Sexton (Yaya DaCosta), Dr. Will Halstead (Nick Gehlfuss) and Dr. Ethan Choi (Brian Tee) treat a racist patient whose strange form of bigotry surprises them all.
Original air date: 01/05/2016 Runtime: 42:15 min. A member of the Firehouse family clings to life and members of the Chicago Med staff discover a highly unusual parallel between cases - a three-part story arc crosses over into "Chicago Fire" and concludes the following night on "Chicago P.D.
Original air date: 01/26/2016 Runtime: 43:02 min. When legal issues complicate matters that stall a life-saving bone marrow transplant, Sharon Goodwin (S. Epatha Merkerson) must decide whether to disobey direct orders or stand by and put a patient's life in jeopardy. April (Yaya DaCosta) tends to a caring, homeless man who Dr. Charles (Oliver Platt) evaluates, only to come to an unusual diagnosis that explains his recent behavior. Dr. Natalie Manning's (Torrey DeVitto) parents (guest stars Michael Hendricks and Regan Rohde) come to town to see their new grandchild, much to the dismay of her mother-in-law, Helen (guest star Annie Potts). Dr. Connor Rhodes (Colin Donnell) treats a couple who are injured on their first date by a hit-and-run driver, who Dr. Halstead (Nick Gehlfuss) discovers has his own reasons for causing the accident.
Original air date: 02/02/2016 Runtime: 42:59 min. Dr. Manning (Torrey DeVitto) returns from maternity leave and helps treat a teen with a long history of medical issues. Dr. Choi (Brian Tee) attends to a former Navy shipmate with a potentially life-threatening ailment and goes above and beyond the scope of his duties to ensure he gets the proper treatment. Saudi Prince Faisal (guest star Lymen Chehade) arrives at the hospital for a planned surgical procedure, but only from Dr. David Downey (guest star Gregg Henry), the hot-shot surgeon who takes a shine to the work of Dr. Rhodes (Colin Donnell). Meanwhile, a budding romance between Sarah (Rachel DiPillo) and hospital lab tech Joey (guest star Peter Mark Kendall) looks hopeful, but April (Yaya DaCosta) might think otherwise.
Original air date: 02/16/2016 Runtime: 42:59 min. A new set of lungs could save his life through an innovative surgical procedure, but an unforeseen medical problem arises with Ray that might derail the doctor's grand plans. Sarah (Rachel DiPillo) contemplates which hospital to select for her residency match while Maggie (Marlyne Barrett) and April (Yaya DaCosta) make their push for her to remain at Chicago Med. Meanwhile, Dr. Choi (Brian Tee) works to determine the cause of an injured teenage star hockey player with an overbearing father while Dr. Halstead (Nick Gehlfuss) and Dr. Manning (Torrey DeVitto) continue to clash.
Original air date: 04/19/2016 Runtime: 42:31 min. An erratic patient comes to the emergency department claiming that his heart is pounding inside his head and takes drastic measures to stop it, leaving Dr. Choi (Brian Tee) and Dr. Charles (Oliver Platt) to figure out the best course of action. Dr. Manning (Torrey DeVitto) works on a young boy with a broken wrist, but her suspicions abound when the facts don't add up, prompting her to report the situation to Goodwin (S. Epatha Merkerson) and Dr. Charles, who must make a serious decision. Dr. Rhodes (Colin Donnell) impresses Dr. Downey (guest star Gregg Henry) with his skills inside the operating room, but the pressure takes a toll. Elsewhere, Will (Nick Gehlfuss) receives news about the pending lawsuit, April (Yaya DaCosta) feels a spark in her social life and Sarah (Rachel DiPillo) tries to determine the cause of her recent anxiety. Marlyne Barrett also stars.